METHODS: case-cohort design looking at 5,679 patients undergoing chest CT. Follow-up was for a median duration of 4.4 years. Cases were defined as patients who subsequently developed a cardiovascular event (n = 493).
RESULTS: Cases were more likely to be older males. Prevalent vertebral fractures increased the risk of a cardiovascular event by about 30%.
CONCLUSION: Prevalent vertebral fractures on routine clinical chest CT are related to future cardiovascular events but do not have additional prognostic value to models that already include age, gender and cardiovascular calcifications.
COMMENT: routine chest CT scans do not provide a coronary artery calcium score. This study may help risk stratify patients when the CAC isn't available.
Int J Cardiovasc Imaging. 2014 Dec 2;